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Product
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Dynamin (Ser774) Antibody
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Cat#
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100-32-70A
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Unit/Weight
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100 μg
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Unit Price
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$381.00
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Species Reactivity
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B, Ck, D, H, Mk, M, R
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Tested Application(s)
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E, IF, IHC, WB
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Brief Description
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Phosphospecific Antibody, Sheep Polyclonal Antibody
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Specific Description
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Dynamin-1 is a microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Dynamin-1 is involved in vesicular trafficking processes, and is involved in receptor-mediated endocytosis. Phosphorylation of Ser774 by GSK3 has been shown to control activity-dependent bulk endocytosis of synaptic vesicles. This antibody is specific for the 95-kDa dynamin protein phosphorylated at Ser774. The antibody detects purified Dynamin phosphorylated in vitro by CdK5 but not by PKC. The antibody does not cross-react with other proteins subtrates of Cdk5 such as amphiphysin and synapsin.
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Storage
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Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
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