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Product
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GluR2 (Ser880) Antibody
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Cat#
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100-32-55A
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Unit/Weight
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100 μg
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Unit Price
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$381.00
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Species Reactivity
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H, M, R, Zf, Ck
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Tested Application(s)
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E, WB
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Brief Description
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Rabbit Polyclonal Antibody, Phosphospecific Antibody
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Specific Description
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The glutamate receptor 2, a homo- or heter0teramer, is an Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The glutamate receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. Ser880 has been identified as a PKC phosphorylation site within the C-terminal region of GluR2 and has been shown to differentially regulate the interaction of the PDZ domain-containing proteins GRIP1 and PICK 1.
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Storage
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Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
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