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Product
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IFNAR1 (Ser535/539) Antibody
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Cat#
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100-32-53A
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Unit/Weight
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100 μg
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Unit Price
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$346.00
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Species Reactivity
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B, D, H, Mk, M, R, Sh
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Tested Application(s)
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E, IHC, WB
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Brief Description
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Phosphospecific Antibody, Rabbit Polyclonal Antibody
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Specific Description
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Interferon-a Receptor, Type I, Subunit I (IFNAR1) associates with IFNAR2 to form the type I interferon receptor. This interferon receptor is a receceptor for interferons alpha and beta. Binding to type I IFNs triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and IFNR alpha- and beta-subunits themselves. IFN receptors are present in all tissues and even on the surface of most IFN-resistant cells. Down regulation of IFNAR1 is influenced by phosphorylation of Serine 535 and 539.
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Storage
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Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
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