|
Product
|
Tryptophan Hydroxylase (Ser19) Antibody
|
|
Cat#
|
100-32-06A
|
|
Unit/Weight
|
100 μg
|
|
Unit Price
|
$381.00
|
|
Species Reactivity
|
B, M, Zf, R
|
|
Tested Application(s)
|
E, WB
|
|
Brief Description
|
Rabbit Polyclonal Antibody, Phosphospecific Antibody
|
|
Specific Description
|
Tryptophan 5-hydroxylase 1 (TPH) catalyzes the following reaction: L-tryptophan + tetrahydrobiopterin + O2 = 5-hydroxy-L-tryptophan + 4a-hydroxytetrahydrobiopterin. TPH belongs to the biopterin-dependent aromatic amino acid hydroxylase family. The activity of TPH is enhanced by phosphorylation by cAMP-dependent protein kinase (PKA) and Ca2+/calmodulin kinase II (CaM K II). CaM K II phosphorylates Ser19 which lies within the regulatory domain of TPH2.
|
|
Storage
|
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
|
|