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Product
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Tryptophan Hydroxylase (Ser260) Antibody
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Cat#
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100-32-05A
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Unit/Weight
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100 μg
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Unit Price
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$381.00
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Species Reactivity
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B, D, Ck, M, Zf, H, R
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Tested Application(s)
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E, WB
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Brief Description
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Rabbit Polyclonal Antibody, Phosphospecific Antibody
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Specific Description
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Tryptophan 5-hydroxylase 1 (TPH) catalyzes the following reaction: L-tryptophan + tetrahydrobiopterin + O2 = 5-hydroxy-L-tryptophan + 4a-hydroxytetrahydrobiopterin. TPH belongs to the biopterin-dependent aromatic amino acid hydroxylase family. The activity of TPH is enhanced by phosphorylation by cAMP-dependent protein kinase (PKA) and Ca2+/calmodulin kinase II (CaM K II). CaM K II phosphorylates Ser260 which lies within the regulatory domain of TPH.
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Storage
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Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
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