Product
|
CD8 (HIT8a) Antibody
|
Cat#
|
100-30-08A
|
Unit/Weight
|
2 ml
|
Unit Price
|
$299.00
|
Species Reactivity
|
H
|
Tested Application(s)
|
FC
|
Brief Description
|
Mouse Monoclonal Antibody, PE-conjugated Antibody
|
Specific Description
|
The CD8 (HIT8a) antibody recognizes a 68-kDa type-I transmembrane glycoprotein that consists of two disulfide-linked chains that form alpha homodimers or alpha/beta heterodimers. The most frequent CD8 antigen is CD8 alpha/beta heterodimer, which is expressed on 13-48 % peripheral blood suppressor/cytotoxic T lymphocytes (Ts/Tc) and 70-80% thymocytes. In addition, a proportion of γδT cells and NK cells express CD8α homodimers. CD8β requires the presence of CD8a to be expressed on the cell surface. CD8 antigen is co-receptor for HLA class-I molecules.
|
Storage
|
Store at 4°C. Product is guaranteed 6 months from the date of shipment.
|
|