MD-2 Monoclonal Antibody

Product   MD-2 Monoclonal Antibody Cat#   100-15-18A Unit/Weight   100 μg Unit Price   $311.00 Species Reactivity   H, M, R Tested Application(s)   E, WB, IHC Brief Description   Pepmic offers MD-2 Monoclonal Antibody product,MD-2 is a member of the Toll/interleukin-1 receptor (TIR) family. Specific Description   MD-2 is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs). TLRs are signaling molecules that recognize different pathogen-associated molecular patterns (PAMPs) and serve as an important link between the innate and adaptive immune responses. TLR4, the major signaling receptor for lipopolysaccharide (LPS), requires the binding of MD-2 to its extracellular region for maximal response to LPS. The specificity of this response is determined by the species of MD-2; e.g., human MD-2 transfected into mouse cells can cause mouse TLR4 to react to LPS analogs that are normally antagonistic to human but not mouse TLR4. Storage   MD-2 monoclonal antibody can be stored at 4°C, stable for one year.