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Product
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KLRA3 Antibody
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Cat#
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100-12-28A
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Unit/Weight
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100 μg
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Unit Price
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$266.00
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Species Reactivity
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M, R
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Tested Application(s)
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E, WB
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Brief Description
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Killer cell lectin-like receptor subfamily A member 3
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Specific Description
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KLRA3 (also known as Ly49C) is a member of the LY49 family of receptors in Natural Killer (NK) cells that bind to major histocompatibility complex (MHC) class 1. These proteins are classified as either activating or inhibitory receptors based on whether they possess an immunoreceptor tyrosine-based inhibitory motif (ITIM) in their cytoplasmic region (for inhibitory receptors), or an immunoreceptor tyrosine-based activation motif (ITAM) that transmits activating signals resulting in phosphorylation of several substrates. KLRA3 is thought to be an inhibitory receptor, recognizing peptide –receptive H-2Kb. This antibody may cross-react with other LY49 receptors.
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Storage
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KLRA3 antibody can be stored at 4°C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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