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Product
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IFN-beta Antibody
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Cat#
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100-12-14A
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Unit/Weight
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100 μg
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Unit Price
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$311.00
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Species Reactivity
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H, M
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Tested Application(s)
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E, WB, IHC
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Brief Description
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Pepmic provided Interferon beta antibody used clinically for treatment of tumors, infections and multiple sclerosis.
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Specific Description
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Type I Interferons (IFN-a/b) are produced primarily in response to viral infection by “Natural IFN-producing cells" (IPCs) as part of the host immune response and can also inhibit the development of tumors. IFN-b binding by its receptor results in the activation of the tyrosine kinases Jak1 and Tyk2 and phosphorylation of members of the STAT family of transcription factors, leading to the transcription and expression of the immune response genes. More recently, several members of the toll-like receptor (TLR) family were found to stimulate the production IFN-b. IFN-b is currently used clinically for treatment of tumors, infections and multiple sclerosis.
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Storage
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IFN-beta antibody can be stored at 4°C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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