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Product
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CCR8 Antibody
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Cat#
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100-6-05A
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Unit/Weight
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100 μg
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Unit Price
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$266.00
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Species Reactivity
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H
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Tested Application(s)
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E, WB
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Brief Description
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Pepmic offers CCR8 Antibody product,CCR8 is one of the chemokine receptors that are required as coreceptors for HIV infection.
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Specific Description
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CCR8 is one of the chemokine receptors that are required as coreceptors for HIV infection. The genes encoding human and murine CCR8 were cloned and designated TER1, CKR-L1, and ChemR1. The encoded seven transmembrane protein was identified as the receptor for human CC chemokine I-309 and renamed CCR8. Recently, CCR8 was found to serve as a coreceptor for diverse T-cell tropic, dual-tropic and macrophage-tropic HIV-1 strains. CCR8 mediates CC chemokine I-309 induced monocyte chemoattraction and HIV-1 envelope fusion and virus infection, which can be prevented by the CCR8 ligand I-309. CCR8 is expressed in spleen, thymus and T lymphoblastic cell lines.
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Storage
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CCR8 antibody can be stored at 4°C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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