|
Product
|
VEGF165, Human(HEK 293-expressed)
|
|
Cat#
|
101-26-16B
|
|
Sequence
|
APMAEGGGQN HHEVVKFMDV YQRSYCHPIE TLVDIFQEYP
DEIEYIFKPS CVPLMRCGGC CNDEGLECVP TEESNITMQI
MRIKPHQGQH IGEMSFLQHN KCECRPKKDR ARQENPCGPC
SERRKHLFVQ DPQTCKCSCK NTDSRCKARQ LELNERTCRC
DKPRR
|
|
Unit/Weight
|
50 μg
|
|
Unit Price
|
$268.00
|
|
Description
|
Vascular Endothelial Growth Factor is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothelial cells, and promotes angiogenesis and vascular permeability. Expressed in vascularized tissues, VEGF plays a prominent role in normal and pathological angiogenesis. Substantial evidence implicates VEGF in the induction of tumor metastasis and intra-ocular neovascular syndromes. VEGF signals through the three receptors; fms-like tyrosine kinase (flt-1), KDR gene product (the mouse homolog of KDR is the flk-1 gene product) and the flt4 gene product.
|
|
Molecular Weight
|
20~26 kDa, observed by reducing SDS-PAGE.
|
|
Purity
|
> 95% as analyzed by SDS-PAGE.
|
|
Storage
|
Lyophilized recombinant Human Vascular Endothelial Growth Factor 165 (VEGF-165) remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, Human Vascular Endothelial Growth Factor 165 (VEGF-165) should be stable up to 1 week at 4°C or up to 2 months at -20°C.
|