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Product
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VEGF165, Rat (CHO-expressed)
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Cat#
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101-26-13B
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Sequence
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APTTEGEQKA HEVVKFMDVY QRSYCRPIET LVDIFQEYPD
EIEYIFKPSC VPLMRCAGCC NDEALECVPT SESNVTMQIM
RIKPHQSQHI GEMSFLQHSR CECRPKKDRT KPENHCEPCS
ERRKHLFVQD PQTCKCSCKN TDSRCKARQL ELNERTCRCD
KPRR
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Unit/Weight
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50 μg
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Unit Price
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$188.00
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Description
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Vascular Endothelial Growth Factor (VEGF) is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothelial cells, and promotes angiogenesis and vascular permeability. Expressed in vascularized tissues, Vascular Endothelial Growth Factor (VEGF) plays a prominent role in normal and pathological angiogenesis. Substantial evidence implicates Vascular Endothelial Growth Factor (VEGF) in the induction of tumor metastasis and intra-ocular neovascular syndromes. Vascular Endothelial Growth Factor (VEGF) signals through the three receptors; fms-like tyrosine kinase (flt-1), KDR gene product (the murine homolog of KDR is the flk-1 gene product) and the flt4 gene product.
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Molecular Weight
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35-48 kDa, observed by non-reducing SDS-PAGE.
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Purity
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> 95% as analyzed by SDS-PAGE and HPLC.
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Storage
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Lyophilized recombinant Rat Vascular Endothelial Growth Factor 165 (VEGF165) remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, rrVEGF165 should be stable up to 1 week at 4°C or up to 2 months at -20°C.
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