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Product
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Human ST-2
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Cat#
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101-11-05A
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Sequence
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His-Tag sequence not included: KFSKQSWGLENEALIVRCPR QGKPSYTVDWYYSQTNKSIP TQERNRVFASGQLLKFLPAA VADSGIYTCIVRSPTFNRTG YANVTIYKKQSDCNVPDYLM YSTVSGSEKNSKIYCPTID LYNWTAPLEWFKNCQALQG SRYRAHKSFLVIDNVMTED AGDYTCKFIHNENGANYSVT ATRSFTVKDEQGFSLFPVI GAPAQNEIKEVEIGKNANL TCSACFGKGTQFLAAVLWQL NGTKITDFGEPRIQQEEGQN QSFSNGLACLDMVLRIADVK EEDLLLQYDCLALNLHGLR RHTVRLSRKNPSKECF
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Unit/Weight
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0.01 mg
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Unit Price
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$228.00
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Description
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The ST2 gene is a member of the IL-1 receptor family, encoding a transmembrane protein with a structure similar to IL-1R1. A soluble form of the protein (ST2) is produced from the same gene by alternative splicing and is reported to be expressed in several cell types including fibroblasts and mast cells. Soluble ST2 has been reported to act as a negative regulator of Th2 cytokine production, and elevated levels have been reported in several disease states and conditions including asthma, sepsis, and myocardial infarction. Recombinant ST2 comprises a 310 amino acid fragment (19-328) corresponding to the soluble ST2 coding sequence and is expressed in E. coli with an amino-terminal hexahistidine tag.
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Molecular Weight
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39.50 kDa
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Purity
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Purity > 95% as determined by reducing and non-reducing SDS-PAGE, Bradford assay, Western blot and ELISA
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Storage
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Store at -20°C. Product is guaranteed one year from the date of shipment.
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