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Product
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PDGF-DD, Human
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Cat#
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101-23-09A
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Sequence
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SYHDRKSKVD LDRLNDDAKR YSCTPRNYSV NIREELKLAN
VVFFPRCLLV QRCGGNCGCG TVNWRSCTCN SGKTVKKYHE
VLQFEPGHIK RRGRAKTMAL VDIQLDHHER CDCICSSRPP
R
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Unit/Weight
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10 μg
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Unit Price
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$78.00
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Description
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PDGF-DD, also known as platelet-derived growth factor D, IEGF and SCDGFB, is asecreted growth factor belonging to the PDGF/VEGFfamily. It is highly expressed in the heart, pancreas, adrenal glands and ovary. PDGF-DD forms functional homodimers that bind and induce PDGF Rβ homodimers and PDGF Rα/β heterodimers that promote intracellular signaling. This plays an important role in the regulation of cell differentiation, migration and survival. It has also been reported that PDGF-DD can induce monocyte and macrophage recruitment, increase interstitial pressure and facilitate wound healing.
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Molecular Weight
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19-21 kDa, observed by reducing SDS-PAGE.
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Purity
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> 95% as analyzed by SDS-PAGE.
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Storage
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Lyophilized recombinant human PDGF-DD remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, human PDGF-DDshould be stable up to 1 week at 4°C or up to 2 months at -20°C.
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