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Product
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PDGF-BB, Human (P. pastoris-expressed)
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Cat#
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101-23-01A
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Sequence
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SLGSLTIAEP AMIAECKTRT EVFEISRRLI DRTNANFLVW
PPCVEVQRCS GCCNNRNVQC RPTQVQLRPV QVRKIEIVRK
KPIFKKATVT LEDHLACKCE TVAAARPVT
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Unit/Weight
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10 μg
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Unit Price
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$88.00
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Description
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Platelet Derived Growth Factor (PDGF) is a potent mitogen for a wide range of cell types including fibroblasts, smooth muscle, connective tissue, bone and cartilage cells, and some blood cells. The PDGF is involved in a number of biological processes, including hyperplasia, chemotaxis, embryonic neuron development, and respiratory tubule epithelial cell development. PDGF which is composed of a dimer of two chains termed the A chain and B chain, can be present as AA or BB homodimers or as an AB heterodimer.Recombinant human Platelet-Derived Growth Factor-BB (rhPDGF-BB) produced in Pichia pastoris is a glycosylated polypeptide. rhPDGF-BB is a 24.3 kDa disulfide-linked homodimer of two B chains (218 total amino acids) and is obtained by proprietary chromatographic techniques at Pepmic.
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Molecular Weight
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24.3kDa, observed by non-reducing SDS-PAGE.
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Purity
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> 97% by SDS-PAGE and HPLC analyses.
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Storage
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Lyophilized recombinant human Platelet-Derived Growth Factor-BB (rhPDGF-BB) remains stable up to 12 months at -80°C from date of receipt. Upon reconstitution, rhPDGF-BB should be stable up to 4 weeks at 4°C or up to 6 months at -20°C.
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