|
Product
|
Kallikrein 1, Human
|
|
Cat#
|
101-32-145A
|
|
Sequence
|
VTEHVLANND VSCDHPSNTV PSGSNQDLGA GAGEDARSDD
SSSRIVGGWE CEQHSQPWQA ALYHFSTFQC GGILVHRQWV
LTAAHCISDN YQLWLGRHNL FDDENTAQFV HVSESFPHPG
FNMSLLENHT RQADEDYSHD LMLLRLTEPA DTITDAVKVV
ELPTEEPEVG STCLASGWGS IEPENFSFPD DLQCVDLKIL
PNDECKKAHV QKVTDFMLCV GHLEGGKDTC VGDSGGPLMC
DGVLQGVTSW GYVPCGTPNK PSVAVRVLSY VKWIEDTIAE
NSHHHHHHHH HH
|
|
Unit/Weight
|
10 μg
|
|
Unit Price
|
$138.00
|
|
Description
|
Kallikrein 1 (KLK1), also known as tissue kallikrein, is a member of the human tissue kallikrein family. Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis, and some have the potential to be used as cancer and other disease biomarkers. Human KLK1 precursor contains a signal peptide (residues 1 to 18), a short pro peptide (residues 19 to 24) and a mature chain (residues 25 to 262).
Recombinant Human Kallikrein 1 produced in CHO cells is a polypeptide chain containing 292 amino acids. A fully biologically active molecule, rhKLK1 has a molecular mass of 46 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques at Pepmic.
|
|
Molecular Weight
|
46 kDa, observed by reducing SDS-PAGE.
|
|
Purity
|
> 95% as analyzed by SDS-PAGE.
|
|
Storage
|
Recombinant Human Kallikrein 1 remains stable up to 6 months at -20°C to -80°C from date of receipt under sterile conditions. Up to 3 months at -20°C to -80 °C under sterile conditions after opening. Avoid repeated freeze-thaw cycles.
|