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Product
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UBE2C/UBCH10, Human
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Cat#
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101-32-136A
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Sequence
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MASQNRDPAA TSVAAARKGA EPSGGAARGP VGKRLQQELM
TLMMSGDKGI SAFPESDNLF KWVGTIHGAA GTVYEDLRYK
LSLEFPSGYP YNAPTVKFLT PCYHPNVDTQ GNICLDILKE
KWSALYDVRT ILLSIQSLLG EPNIDSPLNT HAAELWKNPT
AFKKYLQETY SKQVTSQEP
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Unit/Weight
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10 μg
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Unit Price
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$32.00
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Description
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Ubiquitin璫onjugating Enzyme E2 C(UBE2C), known as Ubiquitin璫onjugating Enzyme H10(UbcH10), is a 179 amino acid(aa) member of the yeast Ubc4/5 family of Ubiquitin璫onjugating(E2) enzymes and has a predicted molecular weight of 19.5 kDa. UbcH10/UBE2C plays a critical role in the destruction of mitotic proteins which is essential for subsequent events in cell cycle progression. UbcH10/UBE2C recognizes TEK sequences in target proteins, mediates Lys11璴inked ubiquitination, and helps promote targeted protein degradation.
Recombinant Human UBE2C produced in E. coli cells is a single non-glycosylated polypeptide chain containing 179 amino acids. A fully biologically active molecule, rhUBE2C has a molecular mass of 19.5 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques at Pepmic.
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Molecular Weight
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19.5 kDa, observed by reducing SDS-PAGE
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Purity
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> 95% as analyzed by SDS-PAGE&HPLC
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Storage
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Lyophilized recombinant Human UBE2C remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, Human UBE2C should be stable up to 1 week at 4°C or up to 3 months at -20°C.
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