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Product
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Sox2-TAT, Human
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Cat#
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101-32-133A
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Sequence
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MYNMMETELK PPGPQQTSGG GGGNSTAAAA GGNQKNSPDR
VKRPMNAFMV WSRGQRRKMA QENPKMHNSE ISKRLGAEWK LLSETEKRPF
IDEAKRLRAL HMKEHPDYKY RPRRKTKTLM KKDKYTLPGG LLAPGGNSMA
SGVGVGAGLG AGVNQRMDSY AHMNGWSNGS YSMMQDQLGY PQHPGLNAHG
AAQMQPMHRY DVSALQYNSM TSSQTYMNGS PTYSMSYSQQ
GTPGMALGSM GSVVKSEASS SPPVVTSSSH SRAPCQAGDL RDMISMYLPG
AEVPEPAAPS RLHMSQHYQS GPVPGTAING TLPLSHMGGY GRKKRRQRRR
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Unit/Weight
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10 μg
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Unit Price
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$52.00
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Description
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Sox2 is a member of the Sox family of transcription factors involved in mammalian development containing a highly conserved 79-residue DNA-binding domain, known as the high mobility group (HMG) box. Sox2 is a transcription factor that forms a trimeric complex with Oct4 and binds to DNA to promote the expression of pluripotent genes involved in self-renewal, while repressing genes involved in cell differentiation. Due to its high pluripotency, Sox2 is a commonly used transcription factor for generating induced-pluripotent stem cells (iPSCs).
Recombinant Human Sox2-TAT produced in HEK293 cells is a polypeptide chain containing 330 amino acids. The rhSox2-TAT has a molecular mass of 50-55 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques at Pepmic.
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Molecular Weight
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50-55 kDa, observed by reducing SDS-PAGE.
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Purity
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> 95% as analyzed by SDS-PAGE.
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Storage
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Lyophilized recombinant HumanSox2-TAT remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, Human Sox2-TAT should be stable up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles.
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