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Product
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KGF/FGF-7, Human(CHO-expressed)
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Cat#
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101-32-95B
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Sequence
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CNDMTPEQMA TNVNCSSPER HTRSYDYMEG GDIRVRRLFC
RTQWYLRIDK RGKVKGTQEM KNNYNIMEIR TVAVGIVAIK
GVESEFYLAM NKEGKLYAKK ECNEDCNFKE LILENHYNTY
ASAKWTHNGG EMFVALNQKG IPVRGKKTKK EQKTAHFLPM
AIT
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Unit/Weight
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25 μg
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Unit Price
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$152.00
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Description
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Keratinocyte Growth Factor (KGF), also known as FGF-7 and HBGF-7, is a mitogen factor belonging to the heparin-binding growth factor family. It is expressed mainly by epithelial cells. KGF binds to fibroblast growth factor receptor 2b (FGFR2b) to form a dimeric complex and initiate downstream signals. KGF plays an important role in embryonic development, cell proliferation and differentiation. It has also been reported to function in kidney and lung development, angiogenesis, wound healing and tumor invasion.
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Molecular Weight
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16-18 kDa, observed by reducing SDS-PAGE.
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Purity
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> 95% as analyzed by SDS-PAGE and HPLC.
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Storage
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Lyophilized recombinant human Keratinocyte Growth Factor(rhKGF) remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, Human Keratinocyte Growth Factor should be stable up to 1 week at 4°C or up to 2 months at -20°C.
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