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Product
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S100A6, His, Human
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Cat#
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101-32-66A
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Sequence
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MHHHHHHMAC PLDQAIGLLV AIFHKYSGRE GDKHTLSKKE
LKELIQKELT IGSKLQDAEI ARLMEDLDRN KDQEVNFQEY
VTFLGALALI YNEALKG
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Unit/Weight
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5 μg
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Unit Price
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$32.00
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Description
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S100 calcium-binding protein A6 (S100A6) is a small calcium binding protein with 2 EF-hand structures and belongs to the S100 family. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 proteins include at least 25 members which are located as a cluster on chromosome 1q21. S100A6 protein may function in stimulation of Ca2+-dependent insulin release, stimulation of prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of this gene have been implicated in melanoma.
Recombinant S100 calcium-binding protein A6 (S100A6) with His tag produced in E. coli is a single chain containing 97 amino acids with molecular mass of 11.1 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques at Pepmic.
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Molecular Weight
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11.1 kDa, observed by reducing SDS-PAGE.
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Purity
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> 95% as analyzed by SDS-PAGE.
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Storage
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Lyophilized recombinant S100 calcium- binding protein A6 (S100A6) remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, S100A6 should be stable up to 2 week at 4°C or up to 3 months at -20°C.
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