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Product
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UBE2B/HR6B, His, Human
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Cat#
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101-32-32B
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Sequence
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MHHHHHHAMG QLRSMSTPAR RRLMRDFKRL QEDPPVGVSG
APSENNIMQW NAVIFGPEGT PFEDGTFKLV IEFSEEYPNK
PPTVRFLSKM FHPNVYADGS ICLDILQNRW SPTYDVSSIL
TSIQSLLDEP NPNSPANSQA AQLYQENKRE YEKRVSAIVE
QSWNDS
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Unit/Weight
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50 μg
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Unit Price
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$62.00
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Description
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Ubiquitin璫onjugating Enzyme E2 B (UBE2B), also referred to as Homolog of Rad6B (HR6B), is a member of the Ubiquitin璫onjugating (E2) enzyme family. It has apredicted molecular weight of 17 kDa, and is highly expressed in the brain, heart, andtestis. UBE2B forms a thioester bond with ubiquitin through a cysteine residue in its catalytic core domain.Studies indicate that UBE2B may play a critical role in male fertility and overexpression may be linked to certain types of cancer.
Recombinant Human UBE2B produced in E. coli cells is a single non-glycosylated polypeptide chain containing 159 amino acids. A fully biologically active molecule, rhUBE2B has a molecular mass of 18.3 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques at Pepmic.
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Molecular Weight
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18.3 kDa, observed by reducing SDS-PAGE.
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Purity
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> 95% as analyzed by SDS-PAGE&HPLC.
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Storage
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Lyophilized recombinant Human UBE2B remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, Human UBE2B should be stable up to 1 week at 4°C or up to 3 months at -20°C.
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