|
Product
|
NRG-1β2, Human
|
|
Cat#
|
101-32-07A
|
|
Sequence
|
SHLVKCAEKE KTFCVNGGEC FMVKDLSNPS RYLCKCPNEF
TGDRCQNYVM ASFYKAEELY Q
|
|
Unit/Weight
|
50 μg
|
|
Unit Price
|
$152.00
|
|
Description
|
Neuregulin is a signaling protein for ErbB2/ErbB4 receptor heterodimers on the cardiac muscle cells, playing an important role in heart structure and function through inducing ErbB2/ErbB4 receptor phosphorylation and cardiomyocyte differentiation. Research on molecular level discovered that recombinant neuregulin could make disturbed myocardial cell structure into order and strengthen the connection between myocardial cells by intercalated discs re-organization.
|
|
Molecular Weight
|
Approximately 7.0 kDa, a single non-glycosylated polypeptide chain containing 61 amino acids.
|
|
Purity
|
> 96 % by SDS-PAGE and HPLC analyses.
|
|
Storage
|
This lyophilized preparation is stable at 2-8 °C, but should be kept at -20 °C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8 °C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 °C to -70 °C. Avoid repeated freeze/thaw cycles.
|
|