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Product
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Angiostatin K1-3, Human
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Cat#
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101-32-05A
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Sequence
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VYLSECKTGN GKNYRGTMSK TKNGITCQKW SSTSPHRPRF
SPATHPSEGL EENYCRNPDN DPQGPWCYTT DPEKRYDYCD
ILECEEECMH CSGENYDGKI SKTMSGLECQ AWDSQSPHAH
GYIPSKFPNK NLKKNYCRNP DRELRPWCFT TDPNKRWELC
DIPRCTTPPP SSGPTYQCLK GTGENYRGNV AVTVSGHTCQ
HWSAQTPHTH NRTPENFPCK NLDENYCRNP DGKRAPWCHT
TNSQVRWEYC KIPSCDSSP
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Unit/Weight
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10 μg
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Unit Price
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$52.00
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Description
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Angiostatin K1-3 is a ~30 kDa fragment of plasminogen that has been shown to act as a potent inhibitor of angiogenesis and tumor growth in vitro and in vivo. Recombinant angiostatin is expressed in E. coli.
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Molecular Weight
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Approximately 29.7 KDa, a single non-glycosylated polypeptide chain containing 259 amino acids.
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Purity
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> 95 % by SDS-PAGE and HPLC analyses.
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Storage
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This lyophilized preparation is stable at 2-8 °C, but should be kept at -20 °C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8 °C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 °C to -70 °C. Avoid repeated freeze/thaw cycles.
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