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Product
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Human Tissue Factor
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Cat#
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101-8-01A
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Sequence
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His-Tag sequence not included: SGTTNTVAAY NLTWKSTNFK TILEWEPKPV NQVYTVQIST KSGDWKSKCF YTTDTECDLT DEIVKDVKQT YLARVFSYPA GNVESTGSAG EPLYENSPEF TPYLETNLGQ PTIQSFEQVG TKVNVTVEDE RTLVRRNNTF LSLRDVFGKD LIYTLYYWKS SSSGKKTAKT NTNEFLIDVD KGENYCFSVQ AVIPSRTVNR KSTDSPVECM GQEKGEFRE
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Unit/Weight
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0.01 mg
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Unit Price
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$228.00
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Description
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Tissue factor is best known as the primary cellular initiator of blood coagulation. After vessel injury, the tissue factor : Factor VIIa complex activates the coagulation protease cascade, which leads to fibrin deposition and activation of platelets. Aberrant tissue factor expression within the vasculature initiates life threatening thrombosis in various diseases, such as sepsis, atherosclerosis, and cancer. Recombinant tissue factor comprises a 219 amino acid fragment (33-251) corresponding to the extracellular domain of tissue factor protein and is expressed in E. coli with an amino-terminal hexahistidine tag.
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Molecular Weight
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29.3 kDa
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Purity
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Purity > 95% as determined by reducing and non-reducing SDS-PAGE, Bradford assay, Western blot and ELISA
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Storage
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Store at -20°C. Product is guaranteed one year from the date of shipment.
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