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Product
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IGF-BP-2, His, Human
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Cat#
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101-22-18B
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Sequence
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FRCPPCTPER LAACGPPPVA PPAAVAAVAG GARMPCAELV
REPGCGCCSV CARLEGEACG VYTPRCGQGL RCYPHPGSEL
PLQALVMGEG TCEKRRDAEY GASPEQVADN GDDHSEGGLV
ENHVDSTMNM LGGGGSAGRK PLKSGMKELA VFREKVTEQH
RQMGKGGKHH LGLEEPKKLR PPPARTPCQQ ELDQVLERIS
TMRLPDERGP LEHLYSLHIP NCDKHGLYNL KQCKMSLNGQ
RGECWCVNPN TGKLIQGAPT IRGDPECHLF YNEQQEARGV
HTQRMQHHHH HH
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Unit/Weight
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50 μg
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Unit Price
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$218.00
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Description
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IGF-BP-2,also known as Insulin-like growth factor-binding protein 2, IBP-2 and BP-2, is a cysteine-rich secreted protein belonging to the IGF-binding protein superfamily. It is expressed by the central nervous system, bone cells and reproductive tissues. IGF-BP-2 binds to both IGF-I and IGF-II, with a much higher binding affinity to IGF-II than IGF-I. IGF-BP-2 has been shown to inhibitand stimulate the growth promoting effects of IGFs, thus serving as a regulator for IGF distribution, function and activity.
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Molecular Weight
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6-20 kDa, observed by reducing SDS-PAGE.
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Purity
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> 95% as analyzed by SDS-PAGE.
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Storage
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Lyophilized recombinant human IGF-BP-2, Hisremains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, human IGF-BP-2, His should be stable up to 1 week at 4°C or up to 2 months at -20°C.
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