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Product
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IGF-I, Human
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Cat#
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101-22-03C
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Sequence
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GPETLCGAEL VDALQFVCGD RGFYFNKPTG YGSSSRRAPQ
TGIVDECCFR SCDLRRLEMY CAPLKPAKSA
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Unit/Weight
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1 mg
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Unit Price
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$118.00
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Description
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Insulin-like growth factor I (IGF-I) also known as Somatamedin C is a hormone similar in molecular structure to insulin. Human IGF-I has two isoforms (IGF-IA and IGF-IB) which is differentially expressed by various tissues. Mature human IGF-I respectively shares 94% and 96% aa sequence identity with mouse and rat IGF-I. Both IGF-I and IGF-II (another ligand of IGF) can signal through the IGF-I receptor (IGFIR), but IGF-II can alone bind the IGF-II receptor (IGFIIR/ Mannose-6-phosphate receptor). IGF-I plays an important role in childhood growth and continues to have anabolic effects in adults.
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Molecular Weight
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7.7 kDa, observed by reducing SDS-PAGE.
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Purity
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> 95% by SDS-PAGE and HPLC analyses.
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Storage
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Lyophilized recombinant human Insulin-like growth factor I (rhIGF-I) remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, rhIGF-I should be stable up to 2 weeks at 4°C or up to 3 months at -20°C.
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