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Product
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GH, Human(CHO-expressed)
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Cat#
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101-29-09B
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Sequence
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FPTIPLSRLF DNASLRAHRL HQLAFDTYQE FEEAYIPKEQ
KYSFLQNPQT SLCFSESIPT PSNREETQQK SNLELLRISL
LLIQSWLEPV QFLRSVFANS LVYGASDSNV YDLLKDLEEG
IQTLMGRLED GSPRTGQIFK QTYSKFDTNS HNDDALLKNY
GLLYCFRKDM DKVETFLRIV QCRSVEGSCG F
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Unit/Weight
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50 μg
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Unit Price
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$318.00
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Description
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Growth hormone (GH), also known as somatotropin, is a member of a family of growth factors that includes prolactin, placental lactogens, proliferins, and somatolactin. It is synthesized primarily by somatotropes in the anterior pituitary and is stored in secretary granules. The pulsatile release of GH into circulation is regulated by the concerted actions of the hypothalamic hormones-GH-releasing hormone (GHRH) and somatostatin (SST) - as well as by signals from the periphery - ghrelin and leptin. The human GH cDNA encodes a 217 amino acid (aa) residue precursor protein with a 26 aa putative signal peptide. By alternative splicing, at least four isoforms of GH have been identified.
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Molecular Weight
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20-24 kDa, observed by non-reducing SDS-PAGE.
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Purity
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> 95% as analyzed by SDS-PAGE and HPLC.
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Storage
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Lyophilized recombinant Human Growth Hormone (GH) remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, rhGH should be stable up to 1 week at 4°C or up to 2 months at -20°C.
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