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Product
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Human Procalcitonin
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Cat#
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101-7-02A
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Sequence
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His-Tag sequence not included: FRSALESSPA DPATLSEDEA RLLLAALVQD YVQMKASELE QEQEREGSSL DSPRSKRCGN LSTCMLGTYT QDFNKFHTFP QTAIGVGAPG KKRDMSSDLE RDHRPHVSMP QNAN
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Unit/Weight
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0.01 mg
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Unit Price
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$228.00
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Description
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Procalcitonin is a peptide hormone mainly produced by the C cells of the thyroid and certain endocrine cells of the lung. Under normal expression conditions, procalcitonin is immediately cleaved into three specific fragments, an N terminal residue, calcitonin and katacalcin. Levels of unprocessed procalcitonin rise significantly after bacterial infection, trauma or shock. Calcitonin causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of these ions in bone. Recombinant procalcitonin comprises a 114 amino acid fragment (3-116) corresponding to the unprocessed procalcitonin protein and is expressed in E. coli with an amino-terminal hexahistidine
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Molecular Weight
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17.34 kDa
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Purity
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Purity > 97% as determined by RP-HPLC and reducing and non-reducing SDS-PAGE. Protein Content determined by UV spectroscopy at 280 nm and quantitation on SDS-PAGE against a known standard.
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Storage
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Store at -20°C. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C. We recommend to add a carrier protein (0.1% HSA or BSA) for long term storage.
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