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Product
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Human Galectin-3
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Cat#
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101-6-05A
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Sequence
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ADNFSLHDALSGSGNPNPQGWPGAWGNQPAGAGGYPGASYPGAYPGQAPP GAYPGQAPPGAYHGAPGAYPGAPAPGVYPGPPSGPGAYPSSGQPSAPGAY PATGPYGAPAGPLIVPYNLPLPGGVVPRMLITILGTVKPNANRIALDFQR GNDVAFHFNPRFNENNRRVI VCNTKLDNNWGREERQSVFPFESGKPFKIQVLVEPDHFKV AVNDAHLLQYNHRVKKLNEISKLGISGDIDLTSASYTMI
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Unit/Weight
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0.05 mg
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Unit Price
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$228.00
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Description
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Recombinant Human Galectin-3 is a member of a large family of carbohydrate-binding proteins. Also known as Mac-2, L29and CBP35, Human Galectin-3 is expressed by a wide range of cell types including activated T-cells, tumor cells, macrophages, osteoclasts, fibroblasts and epithelial cells. Galectin-3 exhibits proinflammatory activities both in vitro and in vivo. Galectin-3 also chemoattracts monocytes and macrophages. Increased circulating levels of Galectin-3 correlate with several types of cancer, suggesting Galectin-3 is involved in tumor growth and metastasis. Human and Mouse Galectin-3 share 80% homology by amino acid sequence. Human Galectin-3 is a recombinant polypeptide chain consisting of 250 amino acids with a MW of 26 kDa.
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Molecular Weight
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26000 Da
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Purity
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Purity > 97% as determined by RP-HPLC and reducing and non-reducing SDS-PAGE. Protein Content determined by UV spectroscopy at 280 nm and quantitation on SDS-PAGE against a known standard.
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Storage
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Store at -20°C. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C. We recommend to add a carrier protein (0.1% HSA or BSA) for long term storage.
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