|
Product
|
Human L-Selectin
|
|
Cat#
|
101-6-03A
|
|
Sequence
|
His-Tag sequence not included: WTYHYSEKPMNWQRARRFCRDNYTDLVAIQNKAEIEYLEK TLPFSRSYYWIGIRKIGGIWTWVGTNKSLTEEGENWGDGEPNNKKNREDC VEIYIKRNKDAGKWNDDACHKLKAALCYTASCQPWSCSGHGECVEIINNY TCNCDVGYYGPQCQFVIQCEPLEAPELGTMDCTHPLGNFSFSSQCAFSCS EGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHPLAS FSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPICQKLDKSFSMIKE GDYN
|
|
Unit/Weight
|
0.01 mg
|
|
Unit Price
|
$228.00
|
|
Description
|
L-Selectin belongs to a family of divalent cation dependent carbohydrate-binding glycoproteins or adhesion molecules. L-Selectin is expressed constitutively on lymphocytes, monocytes and granulocytes and interacts specifically with carbohydrate groups on activated endothelial cells. L-Selectin is shed by proteolytic cleavage and circulating levels in biological fluids are used as an indicator of various pathological conditions. Recombinant human L-selectin comprises a 294 amino acid fragment (39-332) corresponding to the mature L-Selectin extracellular domain and is expressed in E. coli with an amino-terminal hexahistidine tag.
|
|
Molecular Weight
|
37.55 kDa
|
|
Purity
|
Purity > 95% as determined by reducing and non-reducing SDS-PAGE, Bradford assay, Western blot and ELISA
|
|
Storage
|
Store at -20°C. Product is guaranteed one year from the date of shipment.
|