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Product
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G-CSF, Human(CHO-expressed)
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Cat#
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101-21-28B
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Sequence
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TPLGPASSLP QSFLLKCLEQ VRKIQGDGAA LQEKLCATYK
LCHPEELVLL GHSLGIPWAP LSSCPSQALQ LAGCLSQLHS
GLFLYQGLLQ ALEGISPELG PTLDTLQLDV ADFATTIWQQ
MEELGMAPAL QPTQGAMPAF ASAFQRRAGG VLVASHLQSF
LEVSYRVLRH LAQP
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Unit/Weight
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50 μg
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Unit Price
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$268.00
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Description
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Human Granulocyte Colony Stimulating Factor (G-CSF) contains internal disulfide bonds. Among the family of colony-stimulating factors, Granulocyte Colony Stimulating Factor (G-CSF) is the most potent inducer of terminal differentiation to granulocytes and macrophages of leukemic myeloid cell lines. The synthesis of Granulocyte Colony Stimulating Factor (G-CSF) can be induced by bacterial endotoxins, TNF, Interleukin-1 and GM-CSF. Prostaglandin E2 inhibits the synthesis of Granulocyte Colony Stimulating Factor (G-CSF). In epithelial, endothelial, and fibroblastic cells, the secretion of Granulocyte Colony Stimulating Factor (G-CSF) is induced by Interleukin-17.
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Molecular Weight
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18.7kDa, observed by non-reducing SDS-PAGE.
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Purity
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> 95% as analyzed by SDS-PAGE and HPLC.
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Storage
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Lyophilized recombinant human Granulocyte Colony Stimulating Factor (G-CSF) remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, rhG-CSF should be stable up to 1 week at 4°C or up to 2 months at -20°C.
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