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Product
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GM-CSF, Mouse
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Cat#
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101-21-25A
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Sequence
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APTRSPITVT RPWKHVEAIK EALNLLDDMP VTLNEEVEVV
SNEFSFKKLT CVQTRLKIFE QGLRGNFTKL KGALNMTASY
YQTYCPPTPE TDCETQVTTY ADFIDSLKTF LTDIPFECKK
PVQK
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Unit/Weight
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10 μg
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Unit Price
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$78.00
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Description
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Granulocyte Macrophage Colony Stimulating Factor (GM-CSF) was initially characterized as a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. It is produced by a number of different cell types (including activated T cells, B cells, macrophages, mast cells, endothelial cells and fibroblasts) in response to cytokine or immune and inflammatory stimuli. Besides granulocyte-macrophage progenitors, GM-CSF is also a growth factor for erythroid, megakaryocyte and eosinophil progenitors. On mature hematopoietic cells, GM-CSF is a survival factor for and activates the effectors functions of granulocytes, monocytes/macrophages and eosinophils.
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Molecular Weight
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15~19 kDa, observed by non-reducing SDS-PAGE.
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Purity
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> 95% as analyzed by SDS-PAGE and HPLC.
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Storage
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Lyophilized recombinant murine Granulocyte Macrophage Colony Stimulating Factor (GM-CSF) remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, rmGM-CSF should be stable up to 1 week at 4°C or up to 2 months at -20°C.
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