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Product
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M-CSF, Mouse
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Cat#
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101-21-19B
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Sequence
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KEVSEHCSHM IGNGHLKVLQ QLIDSQMETS CQIAFEFVDQ
EQLDDPVCYL KKAFFLVQDI IDETMRFKDN TPNANATERL
QELSNNLNSC FTKDYEEQNK ACVRTFHETP LQLLEKIKNF
FNETKNLLEK DWNIFTKNCN NSFAKCSSRD VVTKP
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Unit/Weight
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50 μg
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Unit Price
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$268.00
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Description
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Macrophage-Colony Stimulating Factor (M-CSF), also known as Colony Stimulating Factor-1 (CSF-1), can stimulate the survival, proliferation and differentiation of mononuclear phagocytes, in addition to the spreading and motility of macrophages[1]. M-CSF is mainly produced by monocytes, macrophages, fibroblasts, and endothelial cells[2]. M-CSF interaction with its receptor, c-fms, has been implicated in the growth, invasion, and metastasis of of several diseases, including breast and endometrial cancers [1][3][4] .
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Molecular Weight
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35-44 kDa, observed by non-reducing SDS-PAGE.
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Purity
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> 95% as analyzed by SDS-PAGE and HPLC.
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Storage
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Lyophilized recombinant murine Macrophage-Colony Stimulating Factor (M-CSF) remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, rmM-CSF should be stable up to 1 week at 4°C or up to 2 months at -20°C.
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