Product
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GM-CSF, RhesusMacaque
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Cat#
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101-21-11B
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Sequence
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APARSPSPGT QPWEHVNAIQ EARRLLNLSR DTAAEMNKTV
EVVSEMFDLQ EPSCLQTRLE LYKQGLQGSL TKLKGPLTMM ASHYKQHCPP
TPETSCATQI ITFQSFKENL KDFLLVIPFD CWEPVQE
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Unit/Weight
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1 mg
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Unit Price
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$2393.00
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Description
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GM-CSF was initially characterized as a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. It is produced by a number of different cell types (including activated T cells, B cells, macrophages, mast cells, endothelial cells and fibroblasts) in response to cytokine or immune and inflammatory stimuli. Besides granulocyte-macrophage progenitors, GM-CSF is also a growth factor for erythroid, megakaryocyte and eosinophil progenitors. On mature hematopoietic cells, GM-CSF is a survival factor for and activates the effector functions of granulocytes, monocytes/macrophages and eosinophils.
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Molecular Weight
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Approximately 14.4 kDa, a single non-glycosylated polypeptide chain containing 127 amino acids.
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Purity
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> 98 % by SDS-PAGE and HPLC analyses.
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Storage
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This lyophilized preparation is stable at 2-8 °C, but should be kept at -20 °C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8 °C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 °C to -70 °C. Avoid repeated freeze/thaw cycles.
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