|
Product
|
GM-CSF, RhesusMacaque
|
|
Cat#
|
101-21-11A
|
|
Sequence
|
APARSPSPGT QPWEHVNAIQ EARRLLNLSR DTAAEMNKTV
EVVSEMFDLQ EPSCLQTRLE LYKQGLQGSL TKLKGPLTMM ASHYKQHCPP
TPETSCATQI ITFQSFKENL KDFLLVIPFD CWEPVQE
|
|
Unit/Weight
|
10 μg
|
|
Unit Price
|
$128.00
|
|
Description
|
GM-CSF was initially characterized as a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. It is produced by a number of different cell types (including activated T cells, B cells, macrophages, mast cells, endothelial cells and fibroblasts) in response to cytokine or immune and inflammatory stimuli. Besides granulocyte-macrophage progenitors, GM-CSF is also a growth factor for erythroid, megakaryocyte and eosinophil progenitors. On mature hematopoietic cells, GM-CSF is a survival factor for and activates the effector functions of granulocytes, monocytes/macrophages and eosinophils.
|
|
Molecular Weight
|
Approximately 14.4 kDa, a single non-glycosylated polypeptide chain containing 127 amino acids.
|
|
Purity
|
> 98 % by SDS-PAGE and HPLC analyses.
|
|
Storage
|
This lyophilized preparation is stable at 2-8 °C, but should be kept at -20 °C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8 °C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 °C to -70 °C. Avoid repeated freeze/thaw cycles.
|
|