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Product
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FGF-17, Human
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Cat#
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101-19-104B
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Sequence
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MTQGENHPSP NFNQYVRDQG AMTDQLSRRQ IREYQLYSRT
SGKHVQVTGR RISATAEDGNKFAKLIVETD TFGSRVRIKG AESEKYICMN
KRGKLIGKPS GKSKDCVFTE IVLENNYTAFQNARHEGWFM AFTRQGRPRQ
ASRSRQNQRE AHFIKRLYQG QLPFPNHAEK QKQFEFVGSAPTRRTKRTRR
PQPLT
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Unit/Weight
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50 μg
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Unit Price
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$152.00
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Description
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Fibroblast Growth Factor-17 (FGF-17) is a heparin binding growth factor that is a member of the FGF family. Proteins of this family play multiple roles in biological functions, including angiogenesis, mitogenesis, cell differentiation and wound repair. FGF-17 plays an important role in organizing and inducing specific patterning at the midbrain/hindbrain junction. FGF-17 is also expressed in the hindgut, parts of thedeveloping skeleton, tail bud, major arteries, and heart. FGF-17 signals through hFGFR1c, 2c, 3c, and 4. FGF-17 signals induce patterning of the embryonic brain.
Recombinant Human FGF-17 produced in E .coli is a single non-glycosylated polypeptide chain containing 195 amino acids. A fully biologically active molecule rhFGF-17 has a molecular mass of 22.6 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques at Pepmic.
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Molecular Weight
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22.6 kDa, observed by reducing SDS-PAGE.
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Purity
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> 95% as analyzed by SDS-PAGE.
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Storage
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Lyophilized recombinant Human Fibroblast Growth Factor-17 (FGF-17) remainsst able up to 6 months at -80°C from date of receipt. Upon reconstitution Human FGF-17 should be stable up to 1 week at 4°C or up to 3 months at -20°C.
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