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Product
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FGF-basic, Mouse
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Cat#
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101-19-41C
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Sequence
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MPALPEDGGA AFPPGHFKDP KRLYCKNGGF FLRIHPDGRV
DGVREKSDPH VKLQLQAEER GVVSIKGVCA NRYLAMKEDG
RLLASKCVTE ECFFFERLES NNYNTYRSRK YSSWYVALKR
TGQYKLGSKT GPGQKAILFL PMSAKS
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Unit/Weight
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1 mg
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Unit Price
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$618.00
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Description
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Fibroblast Growth Factor-basic (FGF-basic), also known as HBGF-2, is a non-glycosylated heparin-binding growth factor that belongs to the FGF family. FGF-basic is present in basement membranes and in the subendothelial extracellular matrix of blood vessels. FGF-basic signals through FGFR1, 2, 3 and 4 that plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration.
Recombinant mouse Fibroblast Growth Factor-basic (rmFGF-basic) produced in E. coli is a single non-glycosylated polypeptide chain containing 146 amino acids. A fully biologically active molecule, rmFGF-basic has a molecular mass of 16.4 kDa analyzed by reducing SDS-PAGE and is obtained by proprietary chromatographic techniques at Pepmic.
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Molecular Weight
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16.4 kDa, observed by reducing SDS-PAGE.
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Purity
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> 95% by SDS-PAGE and HPLC analyses.
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Storage
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Lyophilized recombinant mouse Fibroblast Growth Factor-basic (rmFGF-basic) remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, rmFGF-basic should be stable up to 2 weeks at 4°C or up to 3 months at -20°C.
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