|
Product
|
FGF-18, Human
|
|
Cat#
|
101-19-38C
|
|
Sequence
|
MAEENVDFRI HVENQTRARD DVSRKQLRLY QLYSRTSGKH
IQVLGRRISA RGEDGDKYAQ LLVETDTFGS QVRIKGKETE
FYLCMNRKGK LVGKPDGTSK ECVFIEKVLE NNYTALMSAK
YSGWYVGFTK KGRPRKGPKT RENQQDVHFM KRYPKGQPEL
QKPFKYTTVT KRSR
|
|
Unit/Weight
|
1 mg
|
|
Unit Price
|
$1493.00
|
|
Description
|
Fibroblast Growth Factor-18 (FGF-18) is a heparin-binding growth factor that is a member of the FGF family. FGF-18 signals through FGFR 1c, 2c, 3c, and 4. FGF-18 plays an important role in the regulation of cell proliferation, cell differentiation and cell migration. FGF-18 is required for normal ossification and bone development. It can also stimulate hepatic and intestinal proliferation.
Recombinant human Fibroblast Growth Factor-18 (rhFGF-18) produced in E. coli is a single non-glycosylated polypeptide chain containing 174 amino acids. A fully biologically active molecule, rhFGF-18 has a molecular mass of 20.3 kDa analyzed by reducing SDS-PAGE and is obtained by proprietary chromatographic techniques at Pepmic.
|
|
Molecular Weight
|
20.3 kDa, observed by reducing SDS-PAGE.
|
|
Purity
|
> 95% by SDS-PAGE and HPLC analyses.
|
|
Storage
|
Lyophilized recombinant human Fibroblast Growth Factor-18 (rhFGF-18) remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, rhFGF-18 should be stable up to 2 weeks at 4°C or up to 3 months at -20°C.
|
|