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Product
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FGF-4, Human
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Cat#
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101-19-32B
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Sequence
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MAPTAPNGTL EAELERRWES LVALSLARLP VAAQPKEAAV
QSGAGDYLLG IKRLRRLYCN VGIGFHLQAL PDGRIGGAHA
DTRDSLLELS PVERGVVSIF GVASRFFVAM SSKGKLYGSP
FFTDECTFKE ILLPNNYNAY ESYKYPGMFI ALSKNGKTKK
GNRVSPTMKV THFLPRL
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Unit/Weight
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25 μg
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Unit Price
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$78.00
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Description
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Fibroblast Growth Factor-4 (FGF-4) also known as K-FGF is a heparin-binding growth factor of the FGF family.It was identified by its oncogenic transforming activity. FGF-4 and FGF-3 are located closely on chromosome 11. FGF-4 and its receptors (FGF R1c, 2c, 3c and 4) play an important role in the regulation of embryonic development, cell proliferation, and cell differentiation. FGF-4 is required for normal limb and cardiac valve development during embryogenesis.
Recombinant human Fibroblast Growth Factor-4 (rhFGF-4) produced in E. coli is a single non-glycosylated polypeptide chain containing 177 amino acids. A fully biologically active molecule obtained by proprietary chromatographic techniques at Pepmic, rhFGF-4 has a molecular mass of 19.4kDa as analyzed by reducing SDS-PAGE.
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Molecular Weight
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19.4kDa, observed by reducing SDS-PAGE.
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Purity
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> 95% by SDS-PAGE and HPLC analyses.
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Storage
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Lyophilized recombinant human Fibroblast Growth Factor-4 (rhFGF-4) remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, rhFGF-4 should be stable up to 2 weeks at 4°C or up to 3 months at -20°C.
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