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Product
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FGF-18, Human
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Cat#
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101-19-25A
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Sequence
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AEENVDFRIH VENQTRARDD VSRKQLRLYQ LYSRTSGKHI
QVLGRRISAR GEDGDKYAQL LVETDTFGSQ VRIKGKETEF
YLCMNRKGKL VGKPDGTSKE CVFIEKVLEN NYTALMSAKY
SGWYVGFTKK GRPRKGPKTR ENQQDVHFMK RYPKGQPELQ
KPFKYTTVTK RSRRIRPTHP A
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Unit/Weight
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5 μg
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Unit Price
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$58.00
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Description
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Fibroblast growth factor 18 (FGF18) is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. It has been shown in vitro that this protein is able to induce neurite outgrowth in PC12 cells. Studies of the similar proteins in mouse and chick suggested that this protein is a pleiotropic growth factor that stimulates proliferation in a number of tissues, most notably the liver and small intestine.
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Molecular Weight
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Approximately 21.1 kDa, a single non-glycosylated polypeptide chain containing 181 amino acids.
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Purity
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> 95 % by SDS-PAGE and HPLC analyses.
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Storage
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This lyophilized preparation is stable at 2-8 °C, but should be kept at -20 °C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8 °C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 °C to -70 °C. Avoid repeated freeze/thaw cycles.
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