Product
|
FGF-7, Human
|
Cat#
|
101-19-02A
|
Sequence
|
CNDMTPEQMA TNVNCSSPER HTRSYDYMEG GDIRVRRLFC
RTQWYLRIDK RGKVKGTQEM KNNYNIMEIR TVAVGIVAIK GVESEFYLAM
NKEGKLYAKK ECNEDCNFKE LILENHYNTY ASAKWTHNGG EMFVALNQKG
IPVRGKKTKK EQKTAHFLPM AIT
|
Unit/Weight
|
10 μg
|
Unit Price
|
$152.00
|
Description
|
Keratinocyte Growth Factor-1 (KGF-1/FGF-7) is one of 23 known members of the FGF family. All FGFs have two conserved cysteine residues and share 30 - 50% sequence identity at the amino acid level. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of variety of tissues, by promoting cellular proliferation and differentiation. KGF-1/FG-7 is a mitogen factor specific for epithelial cells and keratinocytes and signals through FGFR 2b. KGF-1/FGF-7 plays a role in kidney and lung development, angiogenesis, and wound healing.
|
Molecular Weight
|
Approximately 18.9 kDa, a single, non-glycosylated polypeptide chain containing 163 amino acids.
|
Purity
|
> 96 % by SDS-PAGE and HPLC analyses.
|
Storage
|
This lyophilized preparation is stable at 2-8 °C, but should be kept at -20 °C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8 °C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 °C to -70 °C. Avoid repeated freeze/thaw cycles.
|
|