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Product
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Human Enolase 2
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Cat#
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101-5-12A
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Sequence
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His-Tag sequence not included: SIEKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGAST GIYEALELRDGDKQRYLGKGVLKAVDHINSTIAPALISSGLSVVEQEKLD NLMLELDGTENKSKFGANAILGVSLAVCKAGAAERELPLYRHIAQLAGNS DLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRDAMRLGAEVYHT LKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYTEKIV IGMDVAASEFYRDGKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVS IEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLL LKVNQIGSVTEAIQACKLAQENGWGVMVSHRSGETEDTFIADLVVGLCTG QIKTGAPCRSERLAKYNQLMRIEEELGDEARFAGHNFRNPSV
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Unit/Weight
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0.01 mg
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Unit Price
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$228.00
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Description
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Enolase 2 (neuronal specific enolase, NSE) is the gamma/gamma isoform of the glycolytic enzyme enolase expressed primarily in neurons, normal and neoplastic neuroendocrine cells. NSE is a highly soluble cytoplasmic protein that is readily secreted into the CSF and serum following tissue damage. NSE shows neurotrophic and neuroprotective properties on a broad spectrum of CNS neurons and binds in a calcium-dependent manner to cultured neocortical neurons promoting cell survival. Recombinant NSE comprises a 433 amino acid fragment (2-434) corresponding to processed mature NSE protein and is expressed in E. coli with an amino-terminal hexahistidine tag.
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Molecular Weight
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51.64 kDa
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Purity
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Purity > 95% as determined by reducing and non-reducing SDS-PAGE, Bradford assay, Western blot and ELISA
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Storage
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Store at -20°C. Product is guaranteed one year from the date of shipment.
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