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Product
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Human THPO
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Cat#
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101-5-03A
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Sequence
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SPAPPACDLR VLSKLLRDSH VLHSRLSQCP EVHPLPTPVL LPAVDFSLGE WKTQMEETKA QDILGAVTLL LEGVMAARGQ LGPTCLSSLL GQLSGQVRLL LGALQSLLGT QLPPQGRTTA HKDPNAIFLS FQHLLRGKVR FLMLVGGSTL CVRRAPPTTA VPSRTSLVLT LNEL
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Unit/Weight
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0.01 mg
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Unit Price
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$228.00
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Description
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Thrombopoietin (THPO) is a lineage-specific cytokine affecting proliferation and maturation of megakaryocytes from their committed progenitor cells. It acts at a late stage of megakaryocyte development, and is a major physiological regulator of circulating platelets. Recombinant Human Thrombopoietin produced in E. coli is a single non-glycosylated polypeptide chain containing 174 amino acids with a MW of 18,608 Da which comprises the receptor binding domain of the Mpl-ligand protein.
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Molecular Weight
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18608 Da
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Purity
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Purity > 98% as determined by analysis by RP-HPLC and reducing and non-reducing SDS-PAGE. Protein Content determined by UV spectroscopy at 280 nm and analysis by RP-HPLC calibrated against a known standard. Quantitation on SDS-PAGE against a known standard.
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Storage
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Store at -20°C. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C. We recommend to add a carrier protein (0.1% HSA or BSA) for long term storage.
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