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Product
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Human TNF-R1
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Cat#
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101-3-05A
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Sequence
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His-Tag sequence not included: DSVCPQGKYIHPQNNSICCTKCHKGTYLYNDCPGPGQDTD CRECESGSFTASENHLRHCLSCSKCRKEMGQVEISSCTVDRDTVCGCRKN QYRHYWSENLFQCFNCSLCLNGTVHLSCQEKQNTVCTCHAGFFLRENECV SCSNCKKSLECTKLCLPQIEN
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Unit/Weight
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0.01 mg
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Unit Price
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$228.00
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Description
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Two types of soluble TNF receptors (sTNF-R1 and sTNF-R2) have been identified which act to neutralize the biological activities of TNF alpha and TNF beta. Levels of these soluble receptors appear to arise as a result of shedding of the extracellular domains of the membrane bound receptors. Elevated levels of soluble TNF receptors have been found in the amniotic fluid of pregnant women. Recombinant sTNF-R1 comprises a 161 amino acid fragment (41-201) corresponding to the mature TNF-R1 protein and is expressed in E. coli with an amino-terminal hexahistidine tag.
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Molecular Weight
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22.68 kDa
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Purity
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Purity > 95% as determined by reducing and non-reducing SDS-PAGE, Bradford assay, Western blot and ELISA.
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Storage
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Store at -20°C. Product is guaranteed one year from the date of shipment.
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