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Product
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IL-3, Human(CHO-expressed)
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Cat#
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101-28-07B
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Sequence
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APMTQTTPLK TSWVNCSNMI DEIITHLKQP PLPLLDFNNL
NGEDQDILME NNLRRPNLEA FNRAVKSLQN ASAIESILKN
LLPCLPLATA APTRHPIHIK DGDWNEFRRK LTFYLKTLEN
AQAQQTTLSL AIF
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Unit/Weight
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50 μg
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Unit Price
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$132.00
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Description
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Interleukin-3 (IL-3) is a hematopoietic growth factor that promotes the survival, differentiation and proliferation of committed progenitor cells of the megakaryocyte, granulocyte-macrophage, erythroid, eosinophil, basophil and mast cell lineages. Produced by T cells, mast cells and eosinophils, IL-3 enhances thrombopoieses, phagocytosis, and antibody-mediated cellular cytotoxicity. Its ability to activate monocytes suggests that IL-3 may have additional immunoregulatory roles. Many of the IL-3 activities depend upon co-stimulation with other cytokines. IL-3 is species-specific, variably glycosylated cytokine.
Recombinant human interleukin 3 expressed in CHO cells is glycosylated protein with molecular weight range from 17 to 30 kDa shown in non-reducing SDS-PAGE.
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Molecular Weight
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17-30 kDa, observed by non-reducing SDS-PAGE.
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Purity
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> 95% as analyzed by SDS-PAGE and HPLC.
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Storage
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Lyophilized recombinant human Interlerkin 3 (IL-3) remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, rhIL-3 should be stable up to 1 week at 4°C or up to 2 months at -20°C.
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