Product
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GCP-2/CXCL6, Human
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Cat#
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101-27-210B
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Sequence
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VLTELRCTCL RVTLRVNPKT IGKLQVFPAG PQCSKVEVVA
SLKNGKQVCL DPEAPFLKKV IQKILDSGNK KN
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Unit/Weight
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25 μg
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Unit Price
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$102.00
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Description
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Granulocyte chemotactic protein 2 (GCP-2) also known as Chemokine (C-X-C motif) ligand 6 (CXCL6) is a small cytokine belonging to the CXC chemokine family. As its former name suggests, GCP-2 is a chemoattractant for neutrophilic granulocytes. Among human CXC chemokines, GCP? is most closely related to ENA?8 (78% amino acid (aa) sequence identity in the mature peptide region and 86% identity in the signal sequence). The structure and sequence of the genes for human GCP? and ENA?8 also exhibit close similarity suggesting the two genes may have originated from a gene duplication. GCP? can signal through the CXCR1 and CXCR2 receptors.
Recombinant human GCP-2/CXCL6 produced in CHO cells is a polypeptide chain containing 72 amino acids. A fully biologically active molecule, rhGCP-2/CXCL6 has a molecular mass of 9 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques at Pepmic.
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Molecular Weight
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9 kDa, observed by reducing SDS-PAGE.
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Purity
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> 98% as analyzed by SDS-PAGE.
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Storage
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Lyophilized recombinant human GCP-2/CXCL6 remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, human GCP-2/CXCL6 should be stable up to 1 week at 4°C or up to 2 months at -20°C.
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