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Product
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LIX/CXCL5 (74aa), Mouse
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Cat#
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101-27-206B
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Sequence
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VIAATELRCV CLTVTPKINP KLIANLEVIP AGPQCPTVEV
IAKLKNQKEV CLDPEAPVIK KIIQKILGSD KKKA
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Unit/Weight
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50 μg
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Unit Price
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$148.00
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Description
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Mouse LIX (C-X-C motif chemokine 5) is a small cytokine belonging to the CXC chemokine family that is cleaved into the following 2 chains [GCP-2(1-78) and GCP-2(9-78)]. Mouse LIX plays a role in reducing sensitivity to sunburn pain in some subjects, and is a potential target which could be used to understand more about pain in other inflammatory conditions. It is most closely related to two highly homologous human neutrophil chemoattractants GCP-2 and ENA-78. The first 78 amino acid residues within the predicted mature mouse LIX shares approximately 61% and 55% amino acid identity with human GCP-2 and ENA-78. This chemokine stimulates the chemotaxis of neutrophils possessing angiogenic properties. It elicits these effects by interacting with the cell surface chemokine receptor CXCR2.
Recombinant mouse LIX/CXCL5 (74aa) produced in CHO cells is a single polypeptide chain containing 74 amino acids. rmLIX/CXCL5(74aa) has a molecular mass of 8 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques at Pepmic.
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Molecular Weight
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8 kDa, observed by reducing SDS-PAGE.
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Purity
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> 98% as analyzed by SDS-PAGE.
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Storage
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Lyophilized recombinant mouse LIX/CXCL5 remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution,mouse LIX/CXCL5 should be stable up to 1 week at 4°C or up to 2 months at -20°C.
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