|
Product
|
DCIP-1/CXCL3, Mouse
|
|
Cat#
|
101-27-203A
|
|
Sequence
|
AVVASELRCQ CLNTLPRVDF ETIQSLTVTP PGPHCTQTEV
IATLKDGQEV CLNPQGPRLQ IIIKKILKSG KSS
|
|
Unit/Weight
|
10 μg
|
|
Unit Price
|
$78.00
|
|
Description
|
Chemokine (C-X-C motif) ligand 3 (CXCL3) is a small cytokine belonging to the CXC chemokine family that is also known as DCIP-1 (dendritic cell inflammatory protein-1) or MIP?b. CXCL3 controls migration and adhesion of monocytes and mediates its effect on its target cell by interacting with cell surface chemokine receptor CXCR2. It has been shown that CXCL3 regulates the migration of precursors of cerebellar granule neurons toward the internal layers of cerebellum, during morphogenesis.
Recombinant mouse DCIP-1/CXCL3 produced in CHO cells is a polypeptide chain containing 73 amino acids. A fully biologically active molecule, rmDCIP-1/CXCL3 has a molecular mass of 8 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques at Pepmic.
|
|
Molecular Weight
|
8 kDa, observed by reducing SDS-PAGE.
|
|
Purity
|
> 98% as analyzed by SDS-PAGE.
|
|
Storage
|
Lyophilized recombinant Mouse DCIP-1/CXCL3 remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, Mouse DCIP-1/CXCL3 should be stable up to 1 week at 4°C or up to 2 months at -20°C.
|