Product
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IL-8/CXCL8 (8-79aa), Human(CHO-expressed)
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Cat#
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101-27-192C
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Sequence
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AVLPRSAKEL RCQCIKTYSK PFHPKFIKEL RVIESGPHCA
NTEIIVKLSD GRELCLDPKE NWVQRVVEKF LKRAENS
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Unit/Weight
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1 mg
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Unit Price
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$1193.00
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Description
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Interleukin-8 (IL-8), also known as CXCL8, GCP-1 and NAP-1, is a proinflammatory chemokine belonging to the intercrine alpha (chemokine CXC) family. It is secreted by monocytes, macrophages and endothelial cells. IL-8 signals through CXCR1 and CXCR2 to chemoattract neutrophils, basophils, and T cells. IL-8 is also a potent promoter of angiogenesis. Other functions of this protein, such as involvement in bronchiolitis pathogenesis, have also been reported.
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Molecular Weight
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~9 kDa, observed by reducing SDS-PAGE
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Purity
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> 95% as analyzed by SDS-PAGE and HPLC.
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Storage
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Lyophilized recombinant Human Interleukin-8 remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, Human Interleukin-8 should be stable up to 1 week at 4°C or up to 2 months at -20°C.
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