|
Product
|
IL-8/CXCL8 (8-79aa), Human(CHO-expressed)
|
|
Cat#
|
101-27-192B
|
|
Sequence
|
AVLPRSAKEL RCQCIKTYSK PFHPKFIKEL RVIESGPHCA
NTEIIVKLSD GRELCLDPKE NWVQRVVEKF LKRAENS
|
|
Unit/Weight
|
50 μg
|
|
Unit Price
|
$152.00
|
|
Description
|
Interleukin-8 (IL-8), also known as CXCL8, GCP-1 and NAP-1, is a proinflammatory chemokine belonging to the intercrine alpha (chemokine CXC) family. It is secreted by monocytes, macrophages and endothelial cells. IL-8 signals through CXCR1 and CXCR2 to chemoattract neutrophils, basophils, and T cells. IL-8 is also a potent promoter of angiogenesis. Other functions of this protein, such as involvement in bronchiolitis pathogenesis, have also been reported.
|
|
Molecular Weight
|
~9 kDa, observed by reducing SDS-PAGE
|
|
Purity
|
> 95% as analyzed by SDS-PAGE and HPLC.
|
|
Storage
|
Lyophilized recombinant Human Interleukin-8 remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, Human Interleukin-8 should be stable up to 1 week at 4°C or up to 2 months at -20°C.
|
|